Faculty of Paramedicine - Ahmad Mirza Agazade Atari

Ahmad Mirza Agazade Atari

Basic Sciences

Academic Position : Lecturer

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Section : Basic Sciences

Educational Background :

Phone : 33361900

Email Address : mirzamaa708@yahoo.com

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Papers Weekly Schedule

Papers

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Article Title : Potentiality and safety assessment of combination therapy with silymarin and celecoxib in osteoarthritis of rat model

Master Auther :

Journal Title and Number : Published by Elsevier Masson SASArticle - Number: 146 -Biomedicine & Preventive Nutrition

Authers : Z. Ashkavanda,∗, H. Malekinejadb, A. Mirza Aghazadehc, J. Aghazade Attari d, B.S. Vishwanatha

Publish : 2013

summary : Osteoarthritis (OA) is a common form of arthritis leading to cartilage degeneration and inflammation. We used rat model to evaluate the protective effect of silymarin (SMN) as a known antioxidant agent individually and in combination with celecoxib (CLX) as a COX-2 inhibitor on MIA-induced arthritis.

Article Title : A NOTE ON SOME RELIABILITY PROPERTIES OF EXTREME VALUE, GENERALIZED PARETO AND TRANSFORMED DISTRIBUTIONS.

Master Auther :

Journal Title and Number : 59 / A Note on some Realiability Properties of Extreme Value, Generalized…. mySCIENCE VII (1-2), 2012, 59-72

Authers : S. Ravi1* and Ahmad Mirza Aghazadeh Attari

Publish : 2012

summary : In this note, we study a few reliability properties of extreme value, generalized Pareto and some transformations of these distributions having positive support. These distributions are used in modelling series and parallel systems when the number of components is large.

Article Title : The Frequency of Consanguineous Marriages and Their Effects on Offsprings in Tabriz City.

Master Auther :

Journal Title and Number : Shiraz E Medical Journal, Vol. 11, No.

Authers : Rahmani SA*, Aboualsoltani F**, Pourbarghi M€, Dolatkhah H±, Mirza Aghazade Aβ.

Publish : 2010

summary : Background: Too much diversity and an ever increasing number of genetic disorders appear as a big challenge in the coming future. One of the main sources of genetic disorders is the consanguineous marriages which are, unfortunately, very common in our society.

Article Title : Investigation of TEL/AML1 and BCR/ABL genes fusion in Acute

Master Auther :

Journal Title and Number : Shiraz E Medical Journal, Vol. 10, No.

Authers : Rahmani SA*, Mehdipour P**, Aboualsoltani F***, Izadyar M§, Zamani M±, Aghazadeh AM¢.

Publish : 2009

summary : Introduction: BCR/ABL fusions in hematopoeitic cells are known to induce resistance to apoptosis and cell changes in response to cell-cell and cell-matrix interactions, on the other hand, patients with TEL/AML1 gene fusions respond differently to treatment, depending on therapeutic protocols.

Article Title : Investigation of TEL/AML1 and BCR/ABL Fusion Genes

Master Auther :

Journal Title and Number : Journal of Sciences, Islamic Republic of Iran 17(1): 17-25 (2006) http://jsciences.ut.ac.ir

Authers : S.A. Rahmani,1,* S.M. Mohadess Ardabili,1 A. Aghazadeh,2 M. Jahani,3 M. Izadyar,4 M. Zamani,5 and P. Mehdipour5

Publish : 2006

summary : A total of sixty patients affected with acute lymphoblastic leukaemia (ALL), including thirty children and thirty adults were studied by the conventional cytogenetics and fluorescence in situ hybridization (FISH) techniques. The TEL, AML1, ABL, and BCR probes were applied on interphase cells prepared from bone marrow samples.

Article Title : IS6110 restriction fragment length polymorphism typing of Mycobacterium tuberculosisisolates from East Azerbaijan

Master Auther :

Journal Title and Number : Mem Inst Oswaldo Cruz, Rio de Janeiro, Vol. 101(5): 517-521, August 2006

Authers : Mohamad Asgharzadeh, Karen Shahbabian*/+, Jafar Majidi, Ahmad Mirza Aghazadeh, Cirus Amini**, Ali Reza Jahantabi*, Abdolnaser Rafi**

Publish : 2006

summary : investigate the genetic variation among Mycobacterium tuberculosis isolates in the East Azerbaijan Province of Iran and to evaluate the level of and risk factors for recent transmission of tuberculosis (TB),

Article Title : Evaluation of glycemic control, gastric juice nitric oxide

Master Auther :

Journal Title and Number : Journal of Medical Genetics and Genomics Vol. 3 (1) pp. 1 – 6

Authers : Homayun Dolatkhah1*, Mohammad Rahbani-Nobar1, Ebrahim Fattahi2, Mohammad Ansari3, Ahmad Mirza-Aghazadeh4, Lida Eftekhari-Vash5, Ashraf Fakhrjo6 and Amir Bahrami7

Publish :

summary : Recently, diabetes mellitus has been known as one of the main cause of upper gastrointestinal symptoms. It has also been suggested that delayed gastric emptying may lead to bacterial overgrowth in the upper gastrointestinal tract.

Article Title : A Unique Report: Development of Super Anti-Human IgG Monoclone with Optical Density Over Than 3

Master Auther : Jafar Majidi

Journal Title and Number : Advanced Pharmaceutical Bulletin, 2013, 3(2), 333-337

Authers : Leili Aghebati Maleki, Behzad Baradaran, Jalal Abdolalizadeh, Fatemeh Ezzatifar, Jafar Majidi

Publish : 2013

summary : Purpose: Monoclonal antibodies and related conjugates are key reagents used in biomedical researches as well as, in treatment, purification and diagnosis of infectious and non- infectious diseases. Methods: Balb/c mice were immunized with purified human IgG. Spleen cells of the most immune mouse were fused with SP2/0 in the presence of Poly Ethylene Glycol (PEG). Supernatant of hybridoma cells was screened for detection of antibody by ELISA. Then, the sample was assessed for cross-reactivity with IgM & IgA by ELISA and confirmed by immunoblotting. The subclasses of the selected mAbs were determined. The best clone was injected intraperitoneally to some pristane-injected mice. Anti-IgG mAb was purified from the animals' ascitic fluid by Ion exchange chromatography and then, mAb was conjugated with HRP. Results: In the present study, over than 50 clones were obtained that 1 clone had optical density over than 3. We named this clone as supermonoclone which was selected for limiting dilution. The result of the immunoblotting, showed sharp band in IgG position and did not show any band in IgM&IgA position. Conclusion: Based on the findings of this study, the conjugated monoclonal antibody could have application in diagnosis of infectious diseases like Toxoplasmosis, Rubella and IgG class of other infectious and non- infectious diseases.

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